Alleviating experimental pulmonary hypertension via co-delivering FoxO1 stimulus and apoptosis activator to hyperproliferating pulmonary arteries

• Main Authors: Bingbing Li (Author), Chao Teng (Author), Huiling Yu (Author), Xiaohong Jiang (Author), Xuyang Xing (Author), Qi Jiang (Author), Chenshi Lin (Author), Zongmin Zhao (Author), Ruifeng Zhang (Author), Wei He (Author)
• Format: Book
• Published: Elsevier, 2023-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Pulmonary hypertension (PH) is an insidious pulmonary vasculopathy with high mortality and morbidity and its underlying pathogenesis is still poorly delineated. The hyperproliferation and apoptosis resistance of pulmonary artery smooth muscle cells (PASMCs) contributes to pulmonary vascular remodeli...