Improved dissolution and bioavailability of silymarin delivered by a solid dispersion prepared using supercritical fluids
The objective of this study was to improve the dissolution and bioavailability of silymarin (SM). Solid dispersions (SDs) were prepared using solution-enhanced dispersion by supercritical fluids (SEDS) and evaluated in vitro and in vivo, compared with pure SM powder. The particle sizes, stability, a...
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Main Authors: | Gang Yang (Author), Yaping Zhao (Author), Nianping Feng (Author), Yongtai Zhang (Author), Ying Liu (Author), Beilei Dang (Author) |
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Format: | Book |
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Elsevier,
2015-06-01T00:00:00Z.
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Online Access: | Connect to this object online. |
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