Histone Demethylase KDM4C Is Required for Ovarian Cancer Stem Cell Maintenance

• Main Authors: Guo-Qing Chen (Author), Ping Ye (Author), Rong-Song Ling (Author), Fa Zeng (Author), Xiong-Shan Zhu (Author), Lu Chen (Author), Yan Huang (Author), Ling Xu (Author), Xiao-Ying Xie (Author)
• Format: Book
• Published: Hindawi Limited, 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Ovarian cancer is a highly deadly disease, which is often diagnosed at a late stage with metastases. However, most ovarian cancers relapse after surgery combined with platinum-based chemotherapy. Cancer stem cells (CSCs) are stem-like cells that possess high tumorigenic capability and display higher...