Validation study of HLA-B*13:01 as a biomarker of dapsone hypersensitivity syndrome in leprosy patients in Indonesia.

• Main Authors: Hana Krismawati (Author), Astrid Irwanto (Author), Arry Pongtiku (Author), Ishak Darryl Irwan (Author), Yustinus Maladan (Author), Yuli Arisanti Sitanggang (Author), Tri Wahyuni (Author), Ratna Tanjung (Author), Yonghu Sun (Author), Hong Liu (Author), Furen Zhang (Author), Antonius Oktavian (Author), Jianjun Liu (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2020-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Leprosy is a stigmatizing, chronic infection which degenerates the nervous system and often leads to incapacitation. Multi-drug therapy which consists of dapsone, rifampicin and clofazimine has been effective to combat this disease. In Indonesia, especially in Papua Island, leprosy is still a proble...