The Bi-(AID-1-T) G-Quadruplex Has a Janus Effect on Primary and Recurrent Gliomas: Anti-Proliferation and Pro-Migration

• Main Authors: Svetlana Pavlova (Author), Lika Fab (Author), Ekaterina Savchenko (Author), Anastasia Ryabova (Author), Marina Ryzhova (Author), Alexander Revishchin (Author), Igor Pronin (Author), Dmitry Usachev (Author), Alexey Kopylov (Author), Galina Pavlova (Author)
• Format: Book
• Published: MDPI AG, 2024-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

High-grade gliomas are considered an incurable disease. Despite all the various therapy options available, patient survival remains low, and the tumor usually returns. Tumor resistance to conventional therapy and stimulation of the migratory activity of surviving cells are the main factors that lead...