Mitochondrial dependent pathway is involved in the protective effects of carboxymethylated chitosan on nitric oxide-induced apoptosis in chondrocytes

• Autors principals: Bin He (Autor), Fei Wu (Autor), Xiaohai Li (Autor), Yang Liu (Autor), Li Fan (Autor), Haohuan Li (Autor)
• Format: Llibre
• Publicat: BMC, 2020-01-01T00:00:00Z.
• Matèries: article
• Accés en línia: Connect to this object online.

Abstract Background Chondrocyte apoptosis activated by the mitochondrial dependent pathway serves a crucial role in cartilage degeneration of osteoarthritis (OA). In the present study, the protective effects of CMCS against sodium nitroprusside (SNP)-induced chondrocyte apoptosis were evaluated and...