2D-QSAR, Docking, Molecular dynamics simulations with the MM/GBSA approaches against Grave's disease and PTPN22

• Main Authors: Emmanuel Israel Edache (Author), Adamu Uzairu (Author), Paul Andrew Mamza (Author), Gideon Adamu Shallangwa (Author)
• Format: Knjiga
• Izdano: Institute for Researches and Community Services Universitas Muhammadiyah Palangkaraya, 2023-08-01T00:00:00Z.
• Teme: article
• Online dostop: Connect to this object online.

Graves' disease (GD) is an autoimmune condition that frequently causes hyperthyroidism and thyrotoxicosis. Protein tyrosine phosphatase, non-receptor type 22 (lymphoid) isoform 1 (PTPN22), is a promising therapeutic candidate for treating Graves' disease, rheumatoid arthritis, type 1 diabe...