Repurposing levocetirizine hydrochloride loaded into cationic ceramide/phospholipid composite (CCPCs) for management of alopecia: central composite design optimization, in- silico and in-vivo studies

• Main Authors: Rofida Albash (Author), Rania Moataz El-Dahmy (Author), Mohammed I. A. Hamed (Author), Khaled M. Darwish (Author), Abdulrahman M. Alahdal (Author), Amira B. Kassem (Author), Abdurrahman M. Fahmy (Author)
• Format: Book
• Published: Taylor & Francis Group, 2022-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Levocetirizine hydrochloride (LVC) is an antihistaminic drug that is repurposed for the treatment of alopecia. This investigation is targeted for formulating LVC into cationic ceramide/phospholipid composite (CCPCs) for the management of alopecia. CCPCs were fabricated by ethanol-injection approach,...