An open label randomized clinical trial comparing the safety and effectiveness of one, two or three weekly pentamidine isethionate doses (seven milligrams per kilogram) in the treatment of cutaneous leishmaniasis in the Amazon Region.

• Main Authors: Ellen Priscilla Nunes Gadelha (Author), Rajendranath Ramasawmy (Author), Bruna da Costa Oliveira (Author), Nágila Morais Rocha (Author), Jorge Augusto de Oliveira Guerra (Author), George Allan Villa Rouco da Silva (Author), Tirza Gabrielle Ramos de Mesquita (Author), Carolina Chrusciak Talhari Cortez (Author), Anette Chrusciak Talhari (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2018-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BACKGROUND:American Cutaneous Leishmaniasis (ACL), a vector borne disease, is caused by various species of Leishmania and in the Amazonas, Leishmania guyanensis is predominant. The recommended drugs for treatment of cutaneous leishmaniasis (CL) in Brazil are pentavalent antimonials, pentamidine iset...