D-Penicillamine: The State of the Art in Humans and in Dogs from a Pharmacological and Regulatory Perspective

• Main Authors: Michela Pugliese (Author), Vito Biondi (Author), Enrico Gugliandolo (Author), Patrizia Licata (Author), Alessio Filippo Peritore (Author), Rosalia Crupi (Author), Annamaria Passantino (Author)
• Format: Book
• Published: MDPI AG, 2021-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Chelant agents are the mainstay of treatment in copper-associated hepatitis in humans, where D-penicillamine is the chelant agent of first choice. In veterinary medicine, the use of D-penicillamine has increased with the recent recognition of copper-associated hepatopathies that occur in several bre...