Effect and Mechanism of Catalpol on Remyelination via Regulation of the NOTCH1 Signaling Pathway

• Main Authors: Yaqin Sun (Author), Jing Ji (Author), Zheng Zha (Author), Hui Zhao (Author), Bing Xue (Author), Liangyun Jin (Author), Lei Wang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Promoting the differentiation of oligodendrocyte precursor cells (OPCs) is important for fostering remyelination in multiple sclerosis. Catalpol has the potential to promote remyelination and exert neuroprotective effects, but its specific mechanism is still unclear. Recent studies have shown that t...