X-ray imaging: A potential enabler of automated particulate detection and cake-structure analysis in lyophilized products?

• Main Authors: Stephan Sacher (Author), Johannes Poms (Author), Michael Dekner (Author), Sabine Wallner-Mang (Author), Martin Vogt (Author), Johannes G. Khinast (Author), Robert Schennach (Author)
• Format: Book
• Published: Elsevier, 2021-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The presence of particulate matter in parenteral products is a major concern since it affects the patients' safety and is one of the main reasons for product recalls. Conventional quality control is based on a visual inspection, which is a labour-intensive task. Limited to clear solutions and t...