Lemon Peel Water Extract: A Novel Material for Retinal Health, Protecting Retinal Pigment Epithelial Cells against Dynamin-Related Protein 1-Mediated Mitochondrial Fission by Blocking ROS-Stimulated Mitogen-Activated Protein Kinase/Extracellular Signal-Regulated Kinase Pathway

• Main Authors: Shang-Chun Tsou (Author), Chen-Ju Chuang (Author), Inga Wang (Author), Tzu-Chun Chen (Author), Jui-Hsuan Yeh (Author), Chin-Lin Hsu (Author), Yu-Chien Hung (Author), Ming-Chung Lee (Author), Yuan-Yen Chang (Author), Hui-Wen Lin (Author)
• Format: Book
• Published: MDPI AG, 2024-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Previous studies showed that NaIO₃ can induce oxidative stress-mediated retinal pigment epithelium (RPE) damage to simulate age-related macular degeneration (AMD). Lemon peel is rich in antioxidants and components that can penetrate the blood-retinal barrier, but their role in...