Synthesis of Two Methotrexate Prodrugs for Optimizing Drug Loading into Liposomes

Synthesis of Two Methotrexate Prodrugs for Optimizing Drug Loading into Liposomes

Methotrexate (MTX), a compound originally used as an anticancer drug, has also found applications in a broad variety of autoimmune disorders thanks to its anti-inflammation and immunomodulatory functions. The broad application of MTX is anyway limited by its poor solubility in biological fluids, its...

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Main Authors: Valentina Di Francesco (Author), Martina Di Francesco (Author), Paolo Decuzzi (Author), Roberto Palomba (Author), Miguel Ferreira (Author)
Format: Book
Published: MDPI AG, 2021-03-01T00:00:00Z.
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3rd Floor Main Library

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