H₂O₂-Mediated Oxidative Stress Enhances Cystathionine γ-Lyase-Derived H₂S Synthesis via a Sulfenic Acid Intermediate

• Main Authors: Jun Wang (Author), Guanya Jia (Author), Heng Li (Author), Shasha Yan (Author), Jing Qian (Author), Xin Guo (Author), Ge Li (Author), Haizhen Qi (Author), Zhilong Zhu (Author), Yanjun Wu (Author), Weijuan He (Author), Weining Niu (Author)
• Format: Book
• Published: MDPI AG, 2021-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Hydrogen sulfide (H₂S), which is generated mainly by cystathionine <i>γ</i>-lyase (CSE) in the cardiovascular system, plays a pivotal role in a wide range of physiological and pathological processes. However, the regulatory mechanism of the CSE/H<sub>2</su...