Validated LCâMS/MS method for simultaneous determination of SIM and its acid form in human plasma and cell lysate: Pharmacokinetic application
Simvastatin (SIM) is a 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor widely used in hyperlipidemia therapy. SIM has recently been studied for its anticancer activity at doses higher than those used for the hyperlipidemia therapy. This prompted us to study the pharmacokinetics of high-dos...
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| Principais autores: | , , , |
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| Formato: | Livro |
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Elsevier,
2012-12-01T00:00:00Z.
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| Número de Chamada: |
A1234.567 |
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| Cópia 1 | Disponível |