Effect of UDP-Glucuronosyltransferase (UGT) 1A Polymorphism (rs8330 and rs10929303) on Glucuronidation Status of Acetaminophen

• Main Authors: Huma Mehboob (Author), Imtiaz Mahmood Tahir (Author), Tahira Iqbal (Author), Sadaf Saleem (Author), Sofia Perveen (Author), Aboubakker Farooqi (Author)
• Format: Book
• Published: SAGE Publishing, 2017-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Interindividual variability in polymorphic uridine diphosphate-glucuronosyltransferase 1A1 (UGT1A1) ascribed to genetic diversity is associated with relative glucuronidation level among individuals. The present research was aimed to study the effect of 2 important single nucleotide polymorphisms (SN...