Environmental Benzopyrene Attenuates Stemness of Placenta-Derived Mesenchymal Stem Cells via Aryl Hydrocarbon Receptor

• Main Authors: June Seok Heo (Author), Ja-Yun Lim (Author), Sangshin Pyo (Author), Dae Wui Yoon (Author), Dongsook Lee (Author), Wen Xiu Ren (Author), Seung Gwan Lee (Author), Gi Jin Kim (Author), Jinkwan Kim (Author)
• Format: Book
• Published: Hindawi Limited, 2019-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The toxic effects of particulate matter have been linked to polycyclic aromatic hydrocarbons (PAHs) such as benzopyrene. PAHs are potent inducers of the aryl hydrocarbon receptor (AhR), which is an expressed nuclear receptor that senses environmental stimuli and modulates gene expression. Even thoug...