Erythropoietin (EPO) Increases Myelin Gene Expression in CG4 Oligodendrocyte Cells through the Classical EPO Receptor

• Main Authors: Ilaria Cervellini (Author), Alexander Annenkov (Author), Thomas Brenton (Author), Yuti Chernajovsky (Author), Pietro Ghezzi (Author), Manuela Mengozzi (Author)
• Format: Book
• Published: BMC, 2013-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Erythropoietin (EPO) has protective effects in neurodegenerative and neuroinflammatory diseases, including in animal models of multiple sclerosis, where EPO decreases disease severity. EPO also promotes neurogenesis and is protective in models of toxic demyelination. In this study, we asked...