Molecular screening of phytocompounds targeting the interface between influenza A NS1 and TRIM25 to enhance host immune responses

• Main Authors: Muhammad Suleman (Author), Abrar Mohammad Sayaf (Author), Abbas Khan (Author), Salman Ali Khan (Author), Norah A. Albekairi (Author), Abdulrahman Alshammari (Author), Abdelali Agouni (Author), Hadi M. Yassine (Author), Sergio Crovella (Author)
• Format: Book
• Published: Elsevier, 2024-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Influenza A virus causes severe respiratory illnesses, especially in developing nations where most child deaths under 5 occur due to lower respiratory tract infections. The RIG-I protein acts as a sensor for viral dsRNA, triggering interferon production through K63-linked poly-ubiquitin...