The role of selective cyclooxygenase isoforms in human intestinal smooth muscle cell stimulated prostanoid formation and proliferation

• Main Authors: Walter E. Longo (Author), Brian Erickson (Author), Ninder Panesar (Author), John E. Mazuski (Author), Sandra Robinson (Author), Donald L. Kaminski (Author)
• Format: Book
• Published: Hindawi Limited, 1998-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Intestinal smooth muscle plays a major role in the repair of injured intestine and contributes to the prostanoid pool during intestinal inflammatory states. Cyclooxygenase (COX), which catalyzes the conversion of arachidonic acid to prostanoids exists in two isoforms, COX-1 and COX-2. The purpose of...