DNA methylation and single-nucleotide polymorphisms in DDX58 are associated with hand, foot and mouth disease caused by enterovirus 71.

• Main Authors: Ya-Ping Li (Author), Chen-Rui Liu (Author), Hui-Ling Deng (Author), Mu-Qi Wang (Author), Yan Tian (Author), Yuan Chen (Author), Yu-Feng Zhang (Author), Shuang-Suo Dang (Author), Song Zhai (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2022-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<h4>Background</h4>This research aimed to explore the association between the RIG-I-like receptor (RIG-I and MDA5 encoded by DDX58 and IFIH1, respectively) pathways and the risk or severity of hand, foot, and mouth disease caused by enterovirus 71 (EV71-HFMD). In this context, we explore...