Impact of altering various image parameters on human epidermal growth factor receptor 2 image analysis data quality

• Main Authors: Liron Pantanowitz (Author), Chi Liu (Author), Yue Huang (Author), Huazhang Guo (Author), Gustavo K Rohde (Author)
• Format: Book
• Published: Elsevier, 2017-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Introduction: The quality of data obtained from image analysis can be directly affected by several preanalytical (e.g., staining, image acquisition), analytical (e.g., algorithm, region of interest [ROI]), and postanalytical (e.g., computer processing) variables. Whole-slide scanners generate digita...