Evaluation of a Methylcellulose and Hyaluronic Acid Hydrogel as a Vehicle for Rectal Delivery of Biologics

• Κύριοι συγγραφείς: Andreea Aprodu (Συγγραφέας), Julia Mantaj (Συγγραφέας), Bahijja Raimi-Abraham (Συγγραφέας), Driton Vllasaliu (Συγγραφέας)
• Μορφή: Βιβλίο
• Έκδοση: MDPI AG, 2019-03-01T00:00:00Z.
• Θέματα: article
• Διαθέσιμο Online: Connect to this object online.

Biologics have changed the management of Inflammatory Bowel Disease (IBD), but there are concerns regarding unexpected systemic toxicity and loss of therapeutic response following administration by injection. Local delivery of biologics directly to the inflamed mucosa via rectal enema administration...