Remyelination-Promoting DNA Aptamer Conjugate Myaptavin-3064 Binds to Adult Oligodendrocytes In Vitro
We previously applied Systematic Evolution of Ligands by EXponential enrichment (SELEX) technology to identify myelin-specific DNA aptamers, using crude mouse central nervous system myelin as bait. This selection identified a 40-nucleotide aptamer (LJM-3064). Multiple biotinylated LJM-3064 molecules...
Saved in:
Main Authors: | Mahboubeh Fereidan-Esfahani (Author), Wei Ying Yue (Author), Brandon Wilbanks (Author), Aaron J. Johnson (Author), Arthur E. Warrington (Author), Charles L. Howe (Author), Moses Rodriguez (Author), Louis J. Maher (Author) |
---|---|
Format: | Book |
Published: |
MDPI AG,
2020-11-01T00:00:00Z.
|
Subjects: | |
Online Access: | Connect to this object online. |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Recent progress of aptamer‒drug conjugates in cancer therapy
by: Jiaxuan He, et al.
Published: (2023) -
Antibodies to Oligodendrocyte Glycoprotein in Children with ADEM
by: J Gordon Millichap
Published: (2010) -
The Regioselective Conjugation of the 15-nt Thrombin Aptamer with an Optimized Tripeptide Sequence Greatly Increases the Anticoagulant Activity of the Aptamer
by: Irina V. Varizhuk, et al.
Published: (2023) -
A Review of Therapeutic Aptamer Conjugates with Emphasis on New Approaches
by: John G. Bruno
Published: (2013) -
The Discovery of RNA Aptamers that Selectively Bind Glioblastoma Stem Cells
by: Alessandra Affinito, et al.
Published: (2019)