Incorporating patient experience into drug development for ulcerative colitis: development of the Urgency Numeric Rating Scale, a patient-reported outcome measure to assess bowel urgency in adults

• Main Authors: Marla C. Dubinsky (Author), Peter M. Irving (Author), Remo Panaccione (Author), April N. Naegeli (Author), Alison Potts-Bleakman (Author), Vipin Arora (Author), Mingyang Shan (Author), Simon Travis (Author)
• Format: Book
• Published: SpringerOpen, 2022-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Bowel urgency, the sudden or immediate need to have a bowel movement, is a common, bothersome and disruptive symptom of ulcerative colitis (UC). UC treatment goals include control of urgency; however, it is not consistently assessed in UC clinical trials. The Urgency Numeric Rati...