Calycosin attenuates renal ischemia/reperfusion injury by suppressing NF-κB mediated inflammation via PPARγ/EGR1 pathway

• Main Authors: Ningxin Zhang (Author), Chen Guan (Author), Zengying Liu (Author), Chenyu Li (Author), Chengyu Yang (Author), Lingyu Xu (Author), Meng Niu (Author), Long Zhao (Author), Bin Zhou (Author), Lin Che (Author), Yanfei Wang (Author), Yan Xu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Renal ischemia reperfusion injury (IRI) is a leading and common cause of acute kidney injury (AKI), and inflammation is a critical factor in ischemic AKI progression. Calycosin (CAL), a major active component of Radix astragali, has been reported to have anti-inflammatory effect in multiple organs....