Translational pharmacokinetic/pharmacodynamic model for mRNA‐0184, an investigational therapeutic for the treatment of heart failure

• Main Authors: Neeraj Kaushal (Author), Husain Attarwala (Author), Mir Javid Iqbal (Author), Rajnish Saini (Author), Linh Van (Author), Min Liang (Author)
• Formato: Livro
• Publicado em: Wiley, 2024-08-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Abstract Heart failure (HF) is a complex, progressive disorder that is associated with substantial morbidity and mortality on a global scale. Relaxin‐2 is a naturally occurring hormone that may have potential therapeutic benefit for patients with HF. To investigate the therapeutic potential of relax...