The downregulation of miR-509-3p expression by collagen type XI alpha 1-regulated hypermethylation facilitates cancer progression and chemoresistance via the DNA methyltransferase 1/Small ubiquitin-like modifier-3 axis in ovarian cancer cells

• المؤلفون الرئيسيون: Yi-Hui Wu (مؤلف), Yu-Fang Huang (مؤلف), Pei-Ying Wu (مؤلف), Tzu-Hao Chang (مؤلف), Soon-Cen Huang (مؤلف), Cheng-Yang Chou (مؤلف)
• التنسيق: كتاب
• منشور في: BMC, 2023-06-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

Abstract Background MicroRNAs are a group of small non-coding RNAs that are involved in development and diseases such as cancer. Previously, we demonstrated that miR-335 is crucial for preventing collagen type XI alpha 1 (COL11A1)-mediated epithelial ovarian cancer (EOC) progression and chemoresista...