A low-frequency IL4R locus variant in Japanese patients with intravenous immunoglobulin therapy-unresponsive Kawasaki disease

• Main Authors: Yuji Amano (Author), Yohei Akazawa (Author), Jun Yasuda (Author), Kazuhisa Yoshino (Author), Katsuhiko Kojima (Author), Norimoto Kobayashi (Author), Satoshi Matsuzaki (Author), Masao Nagasaki (Author), Yosuke Kawai (Author), Naoko Minegishi (Author), Noriko Ishida (Author), Noriko Motoki (Author), Akira Hachiya (Author), Yozo Nakazawa (Author), Masayuki Yamamoto (Author), Kenichi Koike (Author), Toshikazu Takeshita (Author)
• Format: Book
• Published: BMC, 2019-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Kawasaki disease (KD) is a systemic vasculitis which may be associated with coronary artery aneurysms. A notable risk factor for the development of coronary artery aneurysms is resistance to intravenous immunoglobulin (IVIG) therapy, which comprises standard treatment for the acu...