Spray-Dried Amorphous Solid Dispersions of Atorvastatin Calcium for Improved Supersaturation and Oral Bioavailability

• Үндсэн зохиолчид: Jaewook Kwon (Зохиогч), Bhupendra Raj Giri (Зохиогч), Eon Soo Song (Зохиогч), Jinju Bae (Зохиогч), Junseong Lee (Зохиогч), Dong Wuk Kim (Зохиогч)
• Формат: Ном
• Хэвлэсэн: MDPI AG, 2019-09-01T00:00:00Z.
• Нөхцлүүд: article
• Онлайн хандалт: Connect to this object online.

Over the past few decades, the amorphous solid dispersions (ASDs) technique has emerged as a promising strategy to enhance the in vitro/in vivo characteristic of hydrophobic drugs. The low aqueous solubility and poor bioavailability of atorvastatin calcium (ATO), a lipid-lowering drug, present chall...