Linking white and grey matter in schizophrenia: oligodendrocyte and neuron pathology in the prefrontal cortex

• Main Authors: Malin Hoistad (Author), Devorah Segal (Author), Nagahide Takahashi (Author), Takeshi Sakurai (Author), Joseph D Buxbaum (Author), Patrick R Hof (Author)
• Format: Book
• Published: Frontiers Media S.A., 2009-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Neuronal circuitry relies to a large extent on the presence of functional myelin produced in the brain by oligodendrocytes. Schizophrenia has been proposed to arise partly from altered brain connectivity. Brain imaging and neuropathologic studies have revealed changes in white matter and reduction i...