Induction of IL-10 and TGFβ from CD4+CD25+FoxP3+ T Cells Correlates with Parasite Load in Indian Kala-azar Patients Infected with Leishmania donovani.

• Main Authors: Pradyot Bhattacharya (Author), Smriti Ghosh (Author), Sarfaraz Ahmad Ejazi (Author), Mehebubar Rahaman (Author), Krishna Pandey (Author), Vidya Nand Ravi Das (Author), Pradeep Das (Author), Rama Prosad Goswami (Author), Bibhuti Saha (Author), Nahid Ali (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2016-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BACKGROUND:Visceral leishmaniasis (VL) is distinguished by a complex interplay of immune response and parasite multiplication inside host cells. However, the direct association between different immunological correlates and parasite numbers remains largely unknown. METHODOLOGY/PRINCIPAL FINDINGS:We...