A screening pipeline for antiparasitic agents targeting cryptosporidium inosine monophosphate dehydrogenase.

• Main Authors: Lisa Sharling (Author), Xiaoping Liu (Author), Deviprasad R Gollapalli (Author), Sushil K Maurya (Author), Lizbeth Hedstrom (Author), Boris Striepen (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2010-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The protozoan parasite Cryptosporidium parvum is responsible for significant disease burden among children in developing countries. In addition Cryptosporidiosis can result in chronic and life-threatening enteritis in AIDS patients, and the currently available drugs lack efficacy in treating these s...