A screening pipeline for antiparasitic agents targeting cryptosporidium inosine monophosphate dehydrogenase.

• Auteurs principaux: Lisa Sharling (Auteur), Xiaoping Liu (Auteur), Deviprasad R Gollapalli (Auteur), Sushil K Maurya (Auteur), Lizbeth Hedstrom (Auteur), Boris Striepen (Auteur)
• Format: Livre
• Publié: Public Library of Science (PLoS), 2010-08-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

The protozoan parasite Cryptosporidium parvum is responsible for significant disease burden among children in developing countries. In addition Cryptosporidiosis can result in chronic and life-threatening enteritis in AIDS patients, and the currently available drugs lack efficacy in treating these s...