Inhibition of fucosylation by 2-fluorofucose attenuated acetaminophen-induced liver injury via its anti-inflammation and anti-oxidative stress effects

• Главные авторы: Zhaoguo Liu (Автор), Mengjue Tu (Автор), Jianan Shi (Автор), Hong Zhou (Автор), Guoliang Meng (Автор), Jianguo Gu (Автор), Yuqin Wang (Автор)
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• Опубликовано: Frontiers Media S.A., 2022-09-01T00:00:00Z.
• Предметы: article
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Fucosylation is a common glycan terminal modification, which has been reported to be inhibited by 2-fluorofucose (2FF) both in vivo and in vitro. The present study aimed to investigate the effect of 2FF on acetaminophen (APAP)-induced acute liver injury, and further clarified the possible mechanisms...