Inhibition of fucosylation by 2-fluorofucose attenuated acetaminophen-induced liver injury via its anti-inflammation and anti-oxidative stress effects

• Auteurs principaux: Zhaoguo Liu (Auteur), Mengjue Tu (Auteur), Jianan Shi (Auteur), Hong Zhou (Auteur), Guoliang Meng (Auteur), Jianguo Gu (Auteur), Yuqin Wang (Auteur)
• Format: Livre
• Publié: Frontiers Media S.A., 2022-09-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

Fucosylation is a common glycan terminal modification, which has been reported to be inhibited by 2-fluorofucose (2FF) both in vivo and in vitro. The present study aimed to investigate the effect of 2FF on acetaminophen (APAP)-induced acute liver injury, and further clarified the possible mechanisms...