Saikosaponin-d Suppresses COX2 Through p-STAT3/C/EBPβ Signaling Pathway in Liver Cancer: A Novel Mechanism of Action

• Main Authors: Mudan Ren (Author), Eileen McGowan (Author), Yarui Li (Author), Xiaofeng Zhu (Author), Xinlan Lu (Author), Zhanfang Zhu (Author), Yiguang Lin (Author), Shuixiang He (Author)
• Format: Book
• Published: Frontiers Media S.A., 2019-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Saikosaponin-d (SSd) is an active extract from Radix Bupleuri, the dried root from the plant Bupleurum falcatum used in China for thousands of years to treat liver diseases. The SSd extract possesses valuable pharmacological activities including anti-cancer and anti-inflammatory effects; however, th...