Genetic deletion of the ghrelin receptor (GHSR) impairs growth and blunts endocrine response to fasting in Ghsr-IRES-Cre mice

• Asıl Yazarlar: Fiona Peris-Sampedro (Yazar), Iris Stoltenborg (Yazar), Marie V. Le May (Yazar), Jeffrey M. Zigman (Yazar), Roger A.H. Adan (Yazar), Suzanne L. Dickson (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Elsevier, 2021-09-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Objective: The orexigenic hormone ghrelin exerts its physiological effects by binding to and activating the growth hormone secretagogue receptor (GHSR). The recent development of a Ghsr-IRES-Cre knock-in mouse line has enabled to genetically access GHSR-expressing neurons. Inserting a Cre construct...