Supervised Multidimensional Item Response Theory Modeling of Pediatric Iatrogenic Withdrawal Symptoms

• Main Authors: Sebastiaan C. Goulooze (Author), Erwin Ista (Author), Monique van Dijk (Author), Thomas Hankemeier (Author), Dick Tibboel (Author), Catherijne A.J. Knibbe (Author), Elke H.J. Krekels (Author)
• Format: Book
• Published: Wiley, 2019-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Item‐level data from composite scales can be analyzed with pharmacometric item response theory (IRT) models to improve the quantification of disease severity compared with the use of total composite scores. However, regular IRT models assume unidimensionality, which is violated in the scale measurin...