Why 90% of clinical drug development fails and how to improve it?

Ninety percent of clinical drug development fails despite implementation of many successful strategies, which raised the question whether certain aspects in target validation and drug optimization are overlooked? Current drug optimization overly emphasizes potency/specificity using structure‒activit...

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Ngā kaituhi matua: Duxin Sun (Author), Wei Gao (Author), Hongxiang Hu (Author), Simon Zhou (Author)
Hōputu: Pukapuka
I whakaputaina: Elsevier, 2022-07-01T00:00:00Z.
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