Tetrandrine inhibits aldosterone synthesis by covalently targeting CYP11A1 to attenuate hypertension

• Автори: Simeng Chu (Автор), Wei Yang (Автор), Yujie Lu (Автор), Junjie Li (Автор), Jiamin Peng (Автор), Wenjuan Liu (Автор), Min Jiang (Автор), Gang Bai (Автор)
• Формат: Книга
• Опубліковано: Frontiers Media S.A., 2024-06-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

IntroductionTetrandrine (Tet) is the main pharmacological component of Stephania tetrandra S. Moore, which is a well-documented traditional Chinese medicine known for its diuretic and antihypertensive properties. Unraveling the specific targets and mechanisms of Tet involved in inducing diuresis and...