Withaferin A inhibits osteosarcoma cells through inactivation of Notch-1 signalling

Human osteosarcoma cells were treated with withaferin A and the antiproliferative activity was evaluated by the 3-(4, 5 dimethyl-thiazol-2-yl)-2, 5-diphenyltetrazolium bromide (MTT) assays. Real-time RT-PCR and western blot were used to investigate whether the down-regulation of Notch-1 contributes...

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Main Authors: Yang Chen (Author), Xiang-Zhen Han (Author), Wei Wang (Author), Ren-Tao Zhao (Author), Xiao Li (Author)
Format: Book
Published: Bangladesh Pharmacological Society, 2014-08-01T00:00:00Z.
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3rd Floor Main Library

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