Withaferin A inhibits osteosarcoma cells through inactivation of Notch-1 signalling

• Κύριοι συγγραφείς: Yang Chen (Συγγραφέας), Xiang-Zhen Han (Συγγραφέας), Wei Wang (Συγγραφέας), Ren-Tao Zhao (Συγγραφέας), Xiao Li (Συγγραφέας)
• Μορφή: Βιβλίο
• Έκδοση: Bangladesh Pharmacological Society, 2014-08-01T00:00:00Z.
• Θέματα: article
• Διαθέσιμο Online: Connect to this object online.

Human osteosarcoma cells were treated with withaferin A and the antiproliferative activity was evaluated by the 3-(4, 5 dimethyl-thiazol-2-yl)-2, 5-diphenyltetrazolium bromide (MTT) assays. Real-time RT-PCR and western blot were used to investigate whether the down-regulation of Notch-1 contributes...