Orexin A induced increases in rat locus coeruleus neuronal activity are attenuated by systemic administration of OX1R and OX2R antagonists

Since the initial characterisation of the orexin/hypocretin system, the noradrenergic locus coeruleus (LC) has been a key focus due to its high expression of orexin receptors. Direct application of orexin A (OX-A) into the LC increases neural activity, and consequently arousal, attention and analges...

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Main Authors: Christopher M. Holton (Author), Gary Gilmour (Author), Keith A. Wafford (Author)
Format: Book
Published: Elsevier, 2020-09-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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