Orexin A induced increases in rat locus coeruleus neuronal activity are attenuated by systemic administration of OX1R and OX2R antagonists
Since the initial characterisation of the orexin/hypocretin system, the noradrenergic locus coeruleus (LC) has been a key focus due to its high expression of orexin receptors. Direct application of orexin A (OX-A) into the LC increases neural activity, and consequently arousal, attention and analges...
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| Main Authors: | , , |
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| Format: | Book |
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Elsevier,
2020-09-01T00:00:00Z.
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