Efficacy of CU06-1004 via regulation of inflammation and endothelial permeability in LPS-induced acute lung injury

• Main Authors: Yeomyeong Kim (Author), Cho-Rong Bae (Author), Dongyeop Kim (Author), Hyejeong Kim (Author), Sunghye Lee (Author), Haiying Zhang (Author), Minyoung Noh (Author), Young-Myeong Kim (Author), Naoki Mochizuki (Author), Young-Guen Kwon (Author)
• Format: Book
• Published: BMC, 2023-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Acute lung injury (ALI) is a life-threatening condition that fundamentally results from inflammation and edema in the lung. There are no effective treatments available for clinical use. Previously, we found that as a leakage blocker CU06-1004 prevents endothelial barrier disrupti...