CBX2 enhances the progression and TMZ chemoresistance of glioma via EZH2-mediated epigenetic silencing of PTEN expression

• Main Authors: Jian Wang (Author), Bo Yang (Author), Yingzhao Wang (Author), Shuhan Liu (Author), Changkai Ma (Author), Jianmin Piao (Author), Shiqiang Ma (Author), Dehai Yu (Author), Wei Wu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Chromobox (CBX) 2, a member of the CBX protein family and a crucial component of the polycomb repressive complex (PRC), exerts significant influence on the epigenetic regulation of tumorigenesis, including glioma. However, the precise role of CBX2 in glioma has remained elusive. In our study, we obs...