Easy and reliable maximum a posteriori Bayesian estimation of pharmacokinetic parameters with the open‐source R package mapbayr

• Autori principali: Félicien Le Louedec (Autore), Florent Puisset (Autore), Fabienne Thomas (Autore), Étienne Chatelut (Autore), Mélanie White‐Koning (Autore)
• Natura: Libro
• Pubblicazione: Wiley, 2021-10-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Abstract Pharmacokinetic (PK) parameter estimation is a critical and complex step in the model‐informed precision dosing (MIPD) approach. The mapbayr package was developed to perform maximum a posteriori Bayesian estimation (MAP‐BE) in R from any population PK model coded in mrgsolve. The performanc...