Peptidases from Latex of Carica candamarcensis Upregulate COX-2 and IL-1 mRNA Transcripts against Salmonella enterica ser. Typhimurium-Mediated Inflammation

• Main Authors: Maria Taciana Ralph (Author), Ayrles Fernanda Brandão Silva (Author), Dayane Laíse da Silva (Author), Danielle Cristina Oliveira do Nascimento (Author), Diogo Manoel Farias da Silva (Author), Manoel A. Gomes-Filho (Author), Paulo Roberto Eleutério Souza (Author), Joaquim Evêncio-Neto (Author), Márcio Viana Ramos (Author), Carlos Edmundo Salas (Author), José Vitor Lima-Filho (Author)
• Format: Book
• Published: Hindawi Limited, 2014-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The immunomodulatory properties of a mixture of cysteine peptidases (P1G10) obtained from the fruit lattice of Carica candamarcensis were investigated. P1G10 was obtained from fresh latex samples by chromatography in a Sephadex column and initially administered to Swiss mice (n=5; 1 or 10 mg/kg) via...