Gallic acid mitigates diclofenac-induced liver toxicity by modulating oxidative stress and suppressing IL-1β gene expression in male rats

• Main Authors: Mohsen Esmaeilzadeh (Author), Esfandiar Heidarian (Author), Mehrnoosh Shaghaghi (Author), Hoshang Roshanmehr (Author), Mohammad Najafi (Author), Alireza Moradi (Author), Ali Nouri (Author)
• Format: Book
• Published: Taylor & Francis Group, 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Context Diclofenac (DIC) is an NSAID and consumption of this drug creates side effects such as liver injury. Gallic acid (GA), a natural component of many plants, is used as an antioxidant agent. Objective This study assesses the hepatoprotective effects of GA in the rat model of DIC-induced liver t...