Hydroxysafflor Yellow A Exerts Anti-Inflammatory Effects Mediated by SIRT1 in Lipopolysaccharide-Induced Microglia Activation

• Main Authors: Xiude Qin (Author), Juanjuan Chen (Author), Guowei Zhang (Author), Chuanpeng Li (Author), Jinqiang Zhu (Author), Hong Xue (Author), Jinfang Li (Author), Tianxiang Guan (Author), Haotao Zheng (Author), Yu Liu (Author), Haobin Cai (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abnormal microglia activation causes sever neuroinflammation, contributing to the development of many diseases, yet the mechanism remains incompletely unknown. In current study, we identified that Hydroxysafflor yellow A (HYA), a chalcone glycoside derived from Carthamus tinctorius L effectively att...