Melatonin Attenuates Dysregulation of the Circadian Clock Pathway in Mice With CCl4-Induced Fibrosis and Human Hepatic Stellate Cells

Melatonin Attenuates Dysregulation of the Circadian Clock Pathway in Mice With CCl4-Induced Fibrosis and Human Hepatic Stellate Cells

Dysregulation of the circadian clock machinery is a critical mechanism in the pathogenesis of fibrosis. This study aimed to investigate whether the antifibrotic effect of melatonin is associated with attenuation of circadian clock pathway disturbances in mice treated with carbon tetrachloride (CCl4)...

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Main Authors: Bárbara González-Fernández (Author), Diana I. Sánchez (Author), Irene Crespo (Author), Beatriz San-Miguel (Author), Juan Ortiz de Urbina (Author), Javier González-Gallego (Author), María J. Tuñón (Author)
Format: Book
Published: Frontiers Media S.A., 2018-05-01T00:00:00Z.
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